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ARYLSULFATASE B
Descriptors Found:
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DeCS
Descriptor
English
:
N-Acetylgalactosamine-4-Sulfatase
Descriptor
Spanish
:
N-Acetilgalactosamina-4-Sulfatasa
Descriptor
Portuguese
:
N-Acetilgalactosamina-4-Sulfatase
Synonyms
English
:
Arylsulfatase B
Tree Number:
D08.811.277.352.827.070.060
D08.811.277.352.827.180.175.060
Definition
English
:
An arylsulfatase that catalyzes the
hydrolysis
of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of
chondroitin
sulfate and
dermatan sulfate
. A deficiency of this enzyme is responsible for the inherited lysosomal
disease
, Maroteaux-Lamy
syndrome
(
MUCOPOLYSACCHARIDOSIS VI
). EC 3.1.6.12.
Entry Combination - descr/qualif
English
:
N-Acetylgalactosamine-4-Sulfatase
/
deficiency
use
Mucopolysaccharidosis VI
History Note
English
:
99; for ARYLSULFATASE B use CHONDRO-4-SULFATASE 1975-98; use N-ACETYLGALACTOSAMINE-4-SULFATASE (NM) 1988-98
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
33824
Unique Identifier:
D020051
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS